The differential expression of SEMA3F, NRP1 and NRP2 was also evaluated in the GSE26304 dataset, which contains samples from normal, pure DCIS, DCIS + IDC, and IDC patients, with DCIS samples divided into DCIS type I (DCIS I, more prone to becoming invasive) and DCIS type II (DCIS II, less prone to becoming invasive) [62]. This evidence concerns the gene NRP1 and ductal breast carcinoma in situ.