SEMA3F and ductal breast carcinoma in situ: Although no clear difference in SEMA3F expression was detected between the DCIS and IDC groups, SEMA3F expression was significantly upregulated from the normal to DCIS II subgroup, and it was nearly significantly upregulated between the normal and both the DCIS I (more prone to becoming invasive) and invasive (IDC) groups (Fig. 7b; upper left panel).