Considering that SEMA3F positively correlates with an estrogen response and NRP1 positively correlates with the basal-like BC subtype, this could be explained by the fact that NRP1 acts as a co-receptor for many ligands, including those that control survival, migration and invasion, which are particularly important in basal breast cancer, such as VEGF, which leads to tumorigenesis and metastasis [92]. The gene discussed is VEGFA; the disease is breast cancer.