Furthermore, SARS-CoV-2 infection also led to the downregulation of Dicer, XPO5, SRSF3, and hnRNPA3 in mouse lung tissues (Fig. 7j), and overexpression of Dicer, XPO5, SRSF3, and hnRNPA3 in mouse lung tissues partially alleviated SARS-CoV-2-induced pneumonia (Fig. 7k and Supplementary Fig. 7h). The gene discussed is DICER1; the disease is pneumonia.