The STAT3 gene is frequently mutated in hematopoietic neoplasms like T-cell large granular lymphocytic leukemia (T-LGL), PTCL, diffuse large B cell lymphomas (DLBCL), anaplastic large T-cell lymphoma (ALCL), and chronic NK lymphoproliferative disorders (NKTCL).599,602–607. The gene discussed is STAT3; the disease is extranodal nasal NK/T cell lymphoma.