FGFR1 SNVs are rare, with N546K and K656E as the most common mutations identified, and with an unclear consequence, S125L mutation was identified in gallbladder and BC.102,103 The majority of SNVs were identified in FGFR2, which are related to NSCLC, GC and endometrial cancer. The gene discussed is FGFR2; the disease is gastric cancer.