According to the analysis results of the Sangerbox3.0 platform, there is a significant difference in the expression level of S100A9 mRNA in pan-cancer, which is higher in GBM, UCEC, CESC, KIPAN, KIRC, SKCM, BLCA, OV, PAAD, and TCGT datasets, and lower in LGG, BRCA, LUAD, STES, PRAD, HNSC, LIHC, WT, THCA, ALL, LAML, ACC and KICH datasets (Figure 1A). The gene discussed is S100A9; the disease is glioblastoma.