In IHC staining, the expression level of iNOS protein reflecting the infiltration level of M1 macrophages in GBM tissues is not significantly increased compared with its corresponding adjacent tissues (Figure 10A), while the expression level of CD206 protein reflecting the infiltration level of M2 macrophages in GBM tissues is significantly increased compared with its corresponding adjacent tissues (Figure 10B). This evidence concerns the gene MRC1 and glioblastoma.