The RCAS-PDGFB GEMM model displayed the classic features of a low-grade glioma including a loose microcystic pattern (Figure 5B), heterogeneity in cellular density (Figure 5C), the absence of mitosis (Figure 5D), and perineuronal satellitosis at the infiltrating edges of the tumors (Figure 5E). The gene discussed is PDGFB; the disease is central nervous system cancer.