Similar results have been reported in other studies showing that autophagy inhibition reverses chemoresistance in SCLC[31] and that increasing the pH of lysosomes to reduce lysosomal function may be an option for SCLC treatment.[32] In the present study, we found that CDK6 expression was associated with TFEB/TFE3 translocation. Here, TFEB is linked to small cell lung carcinoma.