CXCL8 and neoplasm: Remarkably, consistent with the great immunogenicity caused by the unstable genome profiles of the HRD group,[19] HRD tumor epithelial cells exhibited high expression of immune chemokines that recruit immune cells to mediate antitumor effects, such as CXCL8, CXCL10 and CXCL11 (Table S2, Supporting Information).