Of note, compared to those in the HRP group, CD8+ T cells in HRD tumors were characterized by high expression of chemokine receptor genes such as CXCR6 and CXCR4 (Figure 5A) and were positively associated with cytokine‐cytokine receptor interactions, antigen processing and presentation, and the T‐cell receptor signaling pathway (Figure 5B). This evidence concerns the gene CXCR4 and hypoparathyroidism-retardation-dysmorphism syndrome.