RPS6KB1 and hyperlipidemia: HMF has been reported to display a broad range of biological and pharmacological effects, such as potent anti‐inflammatory, antitumor and neuroprotective effects.[52, 53, 54] Our previous research suggested that HMF can target FKBP38 and mTOR/P70S6K/SREBPs pathway to alleviate HFD‐induced hyperlipidemia.[55] Small‐molecule drugs have the potential to interact with multiple targets and exhibit diverse pharmacological activities.