The endoplasmic reticulum (ER)‐resident stimulator of interferon genes (STING) plays important roles in inflammation and pathogen defense by regulating type I interferon signaling.[6, 7, 8, 9] In addition to these functions, recent studies have highlighted the role of STING in physiological states, such as metabolism and protein synthesis.[10, 11] Activation of STING leads to the inflammation of blood vessels, known as STING‐associated vasculopathy with onset in infancy (SAVI),[12] and notably, the STING signal may be important in vascular biology. This evidence concerns the gene STING1 and STING-associated vasculopathy with onset in infancy.