To study the possible coinfiltration patterns of TLSs across different tumour regions, we performed hierarchical clustering of all acquired tumour and stromal tissues and TLSs with or without GCs, stratified by the frequencies of CD8+ PD1+ T cells, FOXP3+CD8+ T cells, PD-1+CD20+ B cells, and PD1+FOXP3+ Treg cells. The gene discussed is CD8A; the disease is neoplasm.