TIAR downregulates the expression of LoxL1-AS1 by destabilizing LOXL1-AS1, suggesting TIAR with LOXL1-AS1 regulates VM in glioma through the TIAR/LOXL1-AS1/miR-374b-5p/MMP14 axis (97) (Figure 5). The gene discussed is TIAL1; the disease is glioma.