These results independently confirm the ability of 7 to inhibit N-cadherin expression in glioblastoma cells observed in vitro (Figure 3F) and are consistent with recently published data on the ability of TMZ to inhibit GFAP expression in U87 glioblastoma in a murine xenograft model (Bakhtiyari-Ramezani et al., 2024). The gene discussed is GFAP; the disease is glioblastoma.