Immunohistochemical staining of vehicle-treated U87 glioblastoma sections with anti-N-cadherin and anti-GFAP antibodies showed high expression of both markers, whereas administration of 7, its combination with TMZ, and TMZ alone significantly reduced their levels, with the most pronounced effect observed in mice treated with TMZ or combined therapy (Figure 8C). Here, CDH2 is linked to glioblastoma.