Additional analysis of the Chinese Glioma Genome Atlas (CCGA) showed that high expression levels of CDH2 and GFAP genes encoding these proteins were significantly associated with poor survival in patients with recurrent glioma (Figure 8A), and according to the Repository for Molecular BRAin Neoplasia DaTa (REMBRANDT), their overexpression is characteristic of mesenchymal-type glioblastoma cells compared to less aggressive proneural-type glioblastoma cells (Figure 8B). The gene discussed is CDH2; the disease is glioma.