Additionally, other findings suggest that besides being associated with cellular senescence, the AURKA gene can drive tumor progression through the LIN28B-RAN-AURKA signaling pathway (Schnepp et al., 2015), and it also plays a role in maintaining N-MYC stability in MYCN-amplified NB (Otto et al., 2009). The gene discussed is LIN28B; the disease is neuroblastoma.