FN1 and colorectal neoplasm: The intense interaction between Fn membrane protein Fap‐2 and the overexpressed D‐galactose‐β‐(1‐3)‐N‐acetyl‐D‐galactosamine (Gal‐GalNAc) on colorectal tumor cells facilitates Fn colonization and significantly reduces immune checkpoint blockade (ICB) efficacy, as evidenced in clinical samples and animal models [8].