Additionally, high‐dose BBR regulated the interactions from liver cancer immune cells to CD8+ T cells via ligand‐receptor pairs such as CCL3–CCR5, CCL5–CCR5, CXCL6–CXCR6, and SPP1–(ITGA4+ITGB1) (Figure S3B, Supporting Information). The gene discussed is SPP1; the disease is liver cancer.