explored the YTHDC1/miR‐30d/RUNX1 pathway in pancreatic ductal adenocarcinoma, showing that YTHDC1 promotes miR‐30d biosynthesis, which targets RUNX1 to regulate SLC2A1 and HK1 expression, thereby inhibiting aerobic glycolysis. This evidence concerns the gene YTHDC1 and pancreatic ductal adenocarcinoma.