revealed that METTL3 mediates lactylation‐driven m6A modification of JAK1 mRNA in tumour‐infiltrating myeloid (TIM) cells, with YTHDF1 enhancing JAK1 translation and subsequent STAT3 phosphorylation, thus enhancing the immunosuppressive function of TIM cells.171. The gene discussed is JAK1; the disease is neoplasm.