IGHE and Alzheimer disease: 7 y/o African American male with AD STAT3 HIES (c.1144C>T) diagnosed at one y/o. His highest recorded IgE is 9,020 IU/dl, and highest recorded eosinophil count 1,500 cells/μl. Clinical infectious history of recurrent skin abscesses with both MRSA and MSSA, mastoidosis with subdural empyema, and pneumonia. There is also noninfectious history of newborn rash and eczema.