While our findings underscore the importance of Prdm1 in liver cNK cells and ILC1s tumor immune surveillance, it does not be validated in human NK cells, whereas previous studies have found that PRDM1 might inhibit the proliferation and function of human NK cells, or human NK cell derived cancer cells (Smith et al., 2010; Küçük et al., 2011). Here, PRDM1 is linked to cancer.