ADRB3 and type 2 diabetes mellitus: In this sense, this study aims to investigate the association of risk variants inSNPs (rs4994) in the ADRB3 gene;(1799854) in the ABCC8 gene;(rs7901695 and rs12255372) in theTCF7L2 gene, and (rs8050136) in theFTO gene with type 2 diabetes (T2D) in a sample of thepopulation of Santarém, in the state of Pará, in the North Region of Brazil, knownas the Amazon Region, where the rates of T2D are high.