We also detected oxidative stress-related biomarkers, inflammatory cytokines, and potential nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1) and janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathways in the colitis tissues. Here, NFE2L2 is linked to colitis.