Moreover, we also performed Western blot analysis examined the expression level of STING expression in colon cancer cell lines overexpressing miR-181a-2-3p by Western blot assay and found that STING protein expression the expression of STING protein was decreased in SW480 and HT29 cell lines overexpressing miR-181a-2-3p (Figure 3E, 3F). This evidence concerns the gene STING1 and malignant colon neoplasm.