A third study,8 also almost 40 years old, examined lipase and colipase secretion in children with Shwachman-Diamond syndrome and cystic fibrosis (CF), comparing them to children with normal secretion as well as Shwachman-Diamond syndrome/CF patients with fat excretion < 7% of measured fat intake (subjects ate ad lib). This evidence concerns the gene CLPS and Shwachman-Diamond syndrome.