Therefore, it is of interest to investigate the changes in inflammatorybiomarkers Evidence that inflammatory markers play a role in the development as well as severity of Type 2 diabetes mellitus (T2DM).This study has been designed to decipher the involvement of Tumor Necrosis Factor (TNFα), Interleukin-6 (IL-6), Nesfatin-1 and Bloodsugar in the etiopathogenesis of T2DM. Here, NUCB2 is linked to type 2 diabetes mellitus.