In contrast, elevated genetically predicted levels of IL_10, IL_13, and TRAIL were linked to an increased risk of this cancer type (IL_10: OR: 1.27, 95% CI: 1.06-1.53, p=0.012; IL_13: OR: 1.15, 95% CI: 1.06-1.53, p=0.036; TRAIL: OR: 1.15, 95% CI: 1.06-1.53, p=0.043). This evidence concerns the gene TNFSF10 and cancer.