TNF and nasopharyngeal carcinoma: The resulting enriched GO and KEGG pathway terms are shown in Fig. 5C and D. Of note, pathways such as “IL-17 signaling pathway”, “HIF-1 signaling pathway”, and “TNF signaling pathway” emerged as the key enriched pathways (Table S2 and S3), strongly suggesting their involvement in mediating morusin's effects on NPC cells.