SOX12 and metastatic malignant neoplasm in the lymph nodes: The expression of SOX12 is correlated with the malignancy of HCC (such as extracapsular invasion, microvascular invasion, and lymph node metastasis), and higher SOX12 levels are associated with poorer prognosis in HCC patients (overall survival P = .0004, progression-free survival P = .0013).44