Various mechanisms of immunogenetic susceptibility for ABPA, such as HLA-DR restriction and HLA-DQ protection and polymorphisms of the IL-4 receptor α-chain, IL-10, surfactant protein A2, and Toll-like receptors, have been suggested in populations with CF and populations without CF.3 The gene discussed is SFTPA2; the disease is allergic bronchopulmonary aspergillosis.