Recent studies have isolated and purified exosomes from rat bone marrow mesenchymal stem cells (BMMSCs), which were obtained from ATCC (Manassas, USA)) and found that miR-223–3p, which is highly expressed in BMMSCs-derived exosomes, can improve OVA-induced airway remodeling and inflammation in asthma rats by modulating NLRP3-induced ASC/Caspase-1/GSDMD signaling (119). Here, CASP1 is linked to asthma.