These revealed a positive enrichment (overrepresentation) of several pathways commonly associated with cancer, including those linked to cellular proliferation such as MYC (which is a proto-oncogene and transcription factor that is amplified in several cancers) targets and G2M checkpoint, angiogenesis, and epithelial mesenchymal transition, the latter being associated with invasion and metastasis (Figure 3Ci). This evidence concerns the gene MYC and cancer.