The association between total VC intake and CRC-specific mortality appeared to vary based on the mutation status of the KRAS or BRAF genes. Higher VC intake was associated with a suggestive decrease in CRC-specific mortality in individuals with wild-type KRAS and BRAF genes, whereas the association was less clear in cases with either KRAS or BRAF mutations. Here, BRAF is linked to colorectal carcinoma.