Serum CPK (mean of 1235.3 IU/L, ranging from 1552 to 54466), serum LDH (mean of 1111.5 IU/L, ranging from 418 to 2020), and serum myoglobin (mean of 2950 ng/mL, ranging from 533 to 9908) were elevated in five cases with rhabdomyolysis. The gene discussed is PIK3C2A; the disease is rhabdomyolysis.