The absence of staining for S100 (a marker for tumors of nerve cell origin), CD34 (a marker for vascular tumors), and desmin (a marker for malignant smooth muscle and fibroblastic tumors) in the current case supports the diagnosis of MF and rules out the possibility of neuroma, hemangiopericytoma, leiomyosarcoma, and fibrosarcoma, respectively [14]. This evidence concerns the gene DES and leiomyosarcoma.