The subgroup analysis of different cancer types, anti-PD-1/PD-L1 drugs, PD-1/PD-L1 inhibitors (PD-1 or PD-L1), treatment regimens (single PD-1/PD-L1 regimen or combination PD-1/PD-L1 regimen), treatment of control arm, PD-L1 clone, and PD-L1 IHC scoring method was performed. This evidence concerns the gene CD274 and cancer.