TF and neoplasm: In this study, we showed that theFP containing PTX, Tf, and antimiR-135b could reduce cell survivalbetter than the same concentration of PTX as the control in vitro.The results confirmed the ability of FP to penetrate the tumor, inducecell death and inflammation, and regulate gene expression in vivo.It seems that AuNPs serve as multifunctional carriers for targetedtherapy, and detailed investigation with respect to internalizationof the biologically produced AuNPs is needed, and we plan to performit in our future studies.