A study on lung cancer showed that, after investigating the expression of E2A-PBX1 in tumor tissues of 184 patients with non-small cell lung cancer, 12.5% of the patients showed the presence of E2A-PBX1, while the positive rate of E2A-PBX1 in the 13 non-small cell lung cancer cell lines reached 23.1%. The gene discussed is PBX1; the disease is lung carcinoma.