NPPB and aortic valve calcification: Patients tolerated exercise if the procedural risk was low and one of the following parameters was present [4, 6]: very severe aortic stenosis (mean pressure gradient ≥ 60 mmHg or maximum velocity ≥ 5 m/s), severe aortic valve calcification and maximum velocity progression ≥ 0.3 m/s per year according to cardiac computed tomography, and markedly elevated BNP levels (> 3× age- and sex-corrected normal range) verified by multiple tests and without clear explanation.