ALB and neoplasm: Nanocarriers can realize the synergetic chemotherapy of multiple drugs, reduce drug resistance, improve the pharmacokinetics of drugs in vivo, and enhance the anti-tumor effect.380,387,398–400 Albumin paclitaxel combined with gemcitabine is one of the recommended regimens for the treatment of pancreatic cancer, according to NCCN guidelines in clinic.401 Chen et al. designed a micelle for the co-delivery of paclitaxel and phosphorylation of gemcitabine based on the ethylene glycol-polyarginine-polylysine (PEG-pArg-pLys) platform.