The intergroup clustered heat map (Figure 3A) and inter-sample clustered heat map (Figure 3B) of the expression of Acin1 and its related genes were generally consistent (Figure 3), and the top 10 Acin1-related genes expressed in HCC are Slc3a2, Wiz, Srrm2, Akt1, Hnrnpu, Sap18b, Pabpn1, Ddx39b, Eif4a3, and Rnps1. This evidence concerns the gene HNRNPU and hepatocellular carcinoma.