For instance, FAM30A acts as an enabler in acute myeloid leukemia and laryngeal squamous cell carcinoma.13,15 Besides, FAM30A has been identified as a positive prognostic factor in gastric cancer, laryngeal squamous cell carcinoma, and lung adenocarcinoma.12,13 Meanwhile, our research also supports the critical prognostic value of FAM30A as an independent prognostic factor, which indicates that FAM30A could be a prognostic marker for CRC. Here, FAM30A is linked to lung adenocarcinoma.