PDCD1 and neoplasm: In addition, our results also demonstrated that RSL + anti-PD-1 therapy can efficiently decrease the volume and weight of tumors compared with those of either RSL or anti-PD-1 treatment alone, indicating the auxiliary effect of RSL on the antitumor effect of anti-PD-1 treatment in a syngeneic MC-38 tumor mouse model (Figure 3D-3E).