Endometriosis is a chronic, hormone-dependent, and inflammatory condition distinguished by histological lesions caused by the presence of endometrial tissue beyond the limits of the uterine cavity.83 Particularly, 9 out of the 13 total AQPs identified in mammals (AQP1, 2, 3, 4, 5, 6, 8, 9, and 11) have been identified in the human female reproductive system. Here, AQP1 is linked to endometriosis.