Fifth, in HCC patients with microvascular invasion, elevated expression of S100A7 and S100A9 was associated with shorter OS, whereas in HCC patients with no vascular invasion, high expression of S100A1 and S100A5 correlated with longer OS but elevated expression of S100PBP was linked to shorter OS (Figure 9). This evidence concerns the gene S100A9 and hepatocellular carcinoma.