Representative GC patients whose IDH mutation status were correctly predicted according to this model are shown in Fig. 2A and B. Among the 12 patients in which the multivariable model could not be used for accurate prediction, the MRI findings of all patients showed GC without contrast enhancement, necrosis, cystic, change, hemorrhage, or type 2 GC; 1 (8.3%) patient had grade 3 oligodendroglioma, and 3 (25%) patients had grade 2 IDH-mutant astrocytomas, while the remaining 8 (66.7%) patients had IDH-wildtype glioblastomas, which were histologically grade 2 or 3 (molecular glioblastoma). The gene discussed is IDH1; the disease is oligodendroglioma.