[45] found that SYT11 is palmitoylated in neurons, and that this modification targets SYT11 to digitonin-insoluble portions of membranes and protects it from endolysosomal degradation, thereby enhancing the binding of α-synuclein to intracellular membranes and promoting pathological α-synuclein aggregation in PD. This evidence concerns the gene SYT11 and Parkinson disease.