One study has reported that A-to-I editing of focal adhesion kinase (FAK) at specific intron sites on chr8,141,702,274 increases the stability of FAK mRNA and expression of FAK protein to promote mesenchymal traits, migration and invasion of lung adenocarcinoma (LUAD) (Amin et al., 2017). The gene discussed is PTK2; the disease is lung adenocarcinoma.