Non-invasive indexes, such as the alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio, the AST-to-platelet ratio index (APRI), and the Fibrosis-4 Index (FIB-4) could predict liver fibrosis in liver disease to some extent [63,64]. The gene discussed is GPT; the disease is Hepatic fibrosis.