Some of the findings highlighted in this exploratory analysis included pathways that were previously associated with AD, including the complement system (https://doi.org/10.1016/j.neuron.2018.10.031), which was up-regulated in male and female subjects, as well as interleukin-10 and interferon signaling (IL-10), which were only up-regulated in female AD patients (cite: https://doi.org/10.1016/S0531-5565(00)00176-5 and https://doi.org/10.3389/fncel.2022.949340) (Table 1). This evidence concerns the gene IL10 and Alzheimer disease.