CXCL8 and Sepsis: In sepsis-induced ALI of CLP rat models, curcumin demonstrated a decrease in inflammation [decreased TNF-α, IL-8, and macrophage migration inhibitory factor (MIF)], pulmonary edema, inflammation in the bronchoalveolar lavage fluid, and myeloperoxidase (MPO) activity and increased the activity of SOD [137].