A GWAS found that the rs641738 variant, located in the 30 untranslated region of the gene encoding membrane-bound O-acyltransferase-domain-containing 7 (MBOAT7), specifically lysophosphatidylinositol-acyltransferase 1, is associated with an elevated risk of alcoholic cirrhosis. The gene discussed is MBOAT7; the disease is alcoholic liver cirrhosis.