GPX4 and glioblastoma: In glioblastoma multiforme (GBM) cells, FOXP3, belonging to the forkhead box (FOX) family, was found to upregulate the transcription of GPX4, but it also attenuated the degradation of GPX4 mRNA through the linc00857/miR-1290 axis, thereby suppressing ferroptosis and promoting proliferation [164].