In response to oxidants, S-glutathionylation of NF-κB caused negative regulation by interfering with the DNA-binding activities of NF-κB subunits [293], suggesting that S-glutathionylation is an important factor in the regulation of NF-κB in clinical results for non-small-cell lung cancer cells, where NF-κB levels are associated with unfavorable prognosis. Here, NFKB1 is linked to non-small cell lung carcinoma.